Our History

Our History

  • In the late ’90s begin the first research and studies on the measurement of d-ROMs (pro-oxidant component).
  • Developed in 1999 the first experimental model of FRAS, which allowed to perform the test on whole blood in a simple way.
  • In 2000 was developed the model FRAS 2, without printer, mainly made available to Italian researchers (avoiding the need to go through the laboratories).
  • In 2002, the FRAS 3 model was developed, with printer and centrifuge integrated into the instrument. This was the first instrument designed not only for researchers but also for physicians and medical specialists. FRAS 3 started to be sold also outside Italy in the research field and in Universities.
  • In 2005 was developed the FRAS 4 model, to which was added the BAP test for the evaluation of the antioxidant component in order to have a complete assessment of oxidative stress in its pro and anti oxidant components.
  • In 2007 was developed the first software for the interpretation and management of the results of oxidative stress, Win Os Manager.
  • At the beginning of 2009 H&D moved to the new site, located in the immediate vicinity of the city.
  • In 2009, the FRAS 4 Evolvo was developed to allow serum/plasma testing for greater accuracy with a new housing and new internal software.
  • Between 2011 and 2012, H&D internalized the production processes for both instrumentation and reagents, obtaining ISO 9001:2008, UNI EN ISO 9001:2008 and ISO 13485:2003 certifications.
  • In 2012 was developed FRAS 4 Evolvo P, with the introduction of two new tests: the PAT test for the antioxidant component of oxidative stress, precise and executable in only 1 minute (replacing the BAP test, less precise and requiring 5 minutes) and the SAT test to measure the antioxidant component of saliva in 1 minute.
  • MiniSat, a new system for measuring antioxidant potential in saliva using the SAT test, was developed in 2013.
  • In 2014 H&D has obtained the UNI EN ISO 13485:2012 certification.
  • In 2015 was launched FRAS 5, a new system for the evaluation of oxidative stress, where all previous experiences have been carefully applied and improved.
  • In 2016, FRAS Bravo, an essential system for testing blood, was launched and the new software for interpretation and management of oxidative stress results, OB Manager, was developed.
  • In 2018, H&D achieved ISO 9001:2015 and UNI EN ISO 9001:2015 certification.
  • In 2019, we achieved ISO 13485:2016 and UNI EN ISO 13485:2016 certification.
  • In 2020, we developed the WellLife test, a visual test that does not require any instruments relying solely on a colorimetric scale.
  • In 2021, the new search engine for oxidative stress publications, BibliOs, was developed.
La Sede

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H&D s.r.l.
Strada Langhirano n°264/1A
LocalitĂ  Fontanini
43124 Parma (PR)

Telefono(+39) 0521 462607